Uteroglobin/CC10 Antibody

Uteroglobin/CC10 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

IHC, IF, FC, ELISA

Conjugate

Unconjugated

Cat no : 10490-1-AP

Synonyms

CC10, CC16, CCPBP, CCSP, SCGB1A1, UGB, UP 1, UP1, Urinary protein 1, Urine protein 1, Uteroglobin



Tested Applications

Positive IHC detected inmouse lung tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

10490-1-AP targets Uteroglobin/CC10 in IHC, IF, FC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity cow, human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Uteroglobin/CC10 fusion protein Ag0758
Full Name secretoglobin, family 1A, member 1 (uteroglobin)
Calculated molecular weight 10 kDa
Observed molecular weight
GenBank accession number BC004481
Gene symbol SCGB1A1
Gene ID (NCBI) 7356
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Uteroglobin, also known as CC10, is a member of the secretoglobin family of small secreted proteins. It is produced by the nonciliated, nonmucous, secretory epithelial clara cells of the pulmonary airways, was first identified in lung lavage by Singh and colleagues. It has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

Protocols

Product Specific Protocols
IHC protocol for Uteroglobin/CC10 antibody 10490-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Eur Respir J

Tropism of influenza B viruses in human respiratory tract explants and airway organoids.

Authors - Christine H T Bui
cowIHC

J Comp Pathol

Structural Development, Cellular Differentiation and Proliferation of the Respiratory Epithelium in the Bovine Fetal Lung.

Authors - J Drozdowska
humanFC

Lab Invest

Identification of mesenchymal stromal cells in human lung parenchyma capable of differentiating into aquaporin 5-expressing cells.

Authors - Golnaz Karoubi
humanIF

PLoS Pathog

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.

Authors - Murgia Claudio C
humanIHC

Lancet Respir Med

Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures.

Authors - Kenrie P Y Hui

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Tessa (Verified Customer) (02-03-2019)

Used in 20pcw human fetal lung and got nice staining. Looks very specific with low background. Found that it did not require antigen retrieval in cryosections. In fact it turned out better in sections where 10mM Na Citrate buffer at pH6 was not used.

  • Applications: Immunohistochemistry,
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: Human Fetal Lung
No image submitted with review