Product Information
30855-1-PBS targets SETD4 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag33842 Product name: Recombinant human SETD4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-50 aa of BC002898 Sequence: MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNL Predict reactive species |
| Full Name | SET domain containing 4 |
| Calculated Molecular Weight | 440 aa, 50 kDa |
| Observed Molecular Weight | 40 kDa |
| GenBank Accession Number | BC002898 |
| Gene Symbol | SETD4 |
| Gene ID (NCBI) | 54093 |
| RRID | AB_3742378 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9NVD3 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
As a lysine methyl-transferase of histone, SET domain-containing protein 4 (SETD4) has been reported to play a role in cell proliferation by controlling related gene expressions . Limited reports reveal that SETD4 is not only indispensable for embryonic neurogenesis, development and regeneration of pancreatic and intestinal organs, regulation of bone marrow mesenchymal stem cells, and modulation of inflammatory cytokines of macrophages, but also involved in the tumorigenesis, progression, and chemotherapy resistance of various tumors, including liver cancer, breast cancer, lymphoma and Non-small Cell Lung Cancer. (PMID: 35545041, PMID: 36027907, PMID: 37879429)
