Product Information
85702-4-PBS targets SIN1/MAPKAP1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | SIN1/MAPKAP1 fusion protein Ag7753 Predict reactive species |
Full Name | mitogen-activated protein kinase associated protein 1 |
Calculated Molecular Weight | 59 kDa |
Observed Molecular Weight | 65 kDa |
GenBank Accession Number | BC002326 |
Gene Symbol | MAPKAP1 |
Gene ID (NCBI) | 79109 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9BPZ7 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Mitogen-activated protein kinase 2-associated protein 1 (MAPKAP1) is also named as MIP1 and SIN1. SIN1/MAPKAP1 is a major partner of mTORC2, acting as a scaffold and responsible for the substrate specificity of the mTOR catalytic subunit (PMID: 37877351). Besides as a component of MTORC2, MAPKAP1 also functions as MEKK2 and Ras-interacting protein and involves in regulating MEKK2 activation and RAS signaling (PMID: 31773361).