SIRP Alpha/CD172a Recombinant monoclonal antibody, PBS Only

SIRP Alpha/CD172a Uni-rAb® Recombinant Antibody for IF/ICC, Cytometric bead array, Indirect ELISA
Cat No. 83729-3-PBS
Clone No.240789E7

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Cytometric bead array, Indirect ELISA

SIRP Alpha, SIRPA, 240789E7, BIT, Brain Ig-like molecule with tyrosine-based activation motifs

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

83729-3-PBS targets SIRP Alpha/CD172a in IF/ICC, Cytometric bead array, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen

CatNo: Eg0625

Product name: Recombinant Human SIRP alpha/CD172a protein (His Tag)(HPLC verified)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 31-370 aa of NM_080792

Sequence: EEELQVIQPDKSVLVAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNER

Predict reactive species
Full Name signal-regulatory protein alpha
Calculated Molecular Weight55 kDa
GenBank Accession NumberNM_080792
Gene Symbol SIRP Alpha
Gene ID (NCBI) 140885
Conjugate Unconjugated
FormLiquid
Purification MethodProtein A purification
UNIPROT IDP78324
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID: 36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954).

Loading...
||
New chat Able
正在加载,请稍候...