Product Information
85145-3-PBS targets MCT2/SLC16A7 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | MCT2/SLC16A7 fusion protein Ag14201 Predict reactive species |
| Full Name | solute carrier family 16, member 7 (monocarboxylic acid transporter 2) |
| Calculated Molecular Weight | 478 aa, 52 kDa |
| Observed Molecular Weight | 40-52 kDa |
| GenBank Accession Number | BC030693 |
| Gene Symbol | MCT2 |
| Gene ID (NCBI) | 9194 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O60669 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
SLC16A7, also named MCT2, is a proton-coupled monocarboxylate transporter catalyzing the rapid transport across the plasma membrane of many monocarboxylates. It has been reported that SLC16A7 is the primary monocarboxylate transporter in Purkinje cells and can be detected in the brain, cerebellum, liver, and kidney, but not in vascular smooth muscle cells, pericytes, endothelium, heart, lung, or stomach. There are some isoforms of SLC16A7 with bands around 52 kDa and 40-45 kDa in SDS-PAGE. The 80 kDa protein might be a dimer, similar to the papers published. (PMID: 9482213, 15749979, 11291733, 16901736)
