Product Information
87757-1-PBS targets SLC22A3 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
| Calculated Molecular Weight | 61KD |
| Observed Molecular Weight | 61 kDa |
| GenBank Accession Number | NM_021977 |
| Gene Symbol | SLC22A3 |
| Gene ID (NCBI) | 6581 |
| RRID | AB_3745734 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O75751 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Solute carrier family 22 member 3 (SLC22A3) is also named Extraneuronal monoamine transporter (EMT) and Organic cation transporter 3 (OCT3). It belongs to the SLC22 transporter family. SLC22A3 is a high-capacity, low-affinity transporter for the neurotransmitters norepinephrine, epinephrine, dopamine, serotonin, and histamine. SLC22A3 plays important roles in interorgan and interorganism small-molecule communication, and also regulates local and overall homeostasis in the body (PMID: 37626799). OCT3 is more widely expressed than OCT1 and OCT2. OCT3 expression is widespread and can be found in the skeletal muscle, heart, brain, placenta, cornea, retina, iris, liver, kidney, and vascular endothelial cells (PMID: 29309257, PMID: 2169772).
