SLC22A3 Recombinant monoclonal antibody

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• SLC22A3 Recombinant monoclonal antibody (87757-1-RR)

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  WB analysis using 87757-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 87757-1-RR (SLC22A3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

SLC22A3 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 87757-1-RR

Clone No.253195B7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

EMT, EMTH, OCT3

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Tested Applications

• Positive WB detected in: mouse kidney tissue, human kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

87757-1-RR targets SLC22A3 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: solute carrier family 22 (extraneuronal monoamine transporter), member 3
• Calculated Molecular Weight: 61KD
• Observed Molecular Weight: 61 kDa
• GenBank Accession Number: NM_021977
• Gene Symbol: SLC22A3
• Gene ID (NCBI): 6581
• RRID: AB_3745734
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O75751
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Solute carrier family 22 member 3 (SLC22A3) is also named Extraneuronal monoamine transporter (EMT) and Organic cation transporter 3 (OCT3). It belongs to the SLC22 transporter family. SLC22A3 is a high-capacity, low-affinity transporter for the neurotransmitters norepinephrine, epinephrine, dopamine, serotonin, and histamine. SLC22A3 plays important roles in interorgan and interorganism small-molecule communication, and also regulates local and overall homeostasis in the body (PMID: 37626799). OCT3 is more widely expressed than OCT1 and OCT2. OCT3 expression is widespread and can be found in the skeletal muscle, heart, brain, placenta, cornea, retina, iris, liver, kidney, and vascular endothelial cells (PMID: 29309257, PMID: 2169772).