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SLC24A6 Polyclonal antibody, PBS Only

SLC24A6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 21430-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

21430-1-PBS targets SLC24A6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag16034

Product name: Recombinant human SLC24A6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 240-333 aa of BC098360

Sequence: YVVTVILCTWIYQRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLP

Predict reactive species
Full Name solute carrier family 24 (sodium/potassium/calcium exchanger), member 6
Calculated Molecular Weight 584 aa, 64 kDa
Observed Molecular Weight 64 kDa
GenBank Accession NumberBC098360
Gene Symbol SLC24A6
Gene ID (NCBI) 80024
RRIDAB_10858637
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6J4K2
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

SLC24A6, also named as NCLX, is a kind of mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion by mediating the exchange of 3 sodium ions per 1 calcium ion. It has been reported that SLC24A6 plays a key role in attenuating potential ROS production and injury upon cardiac reperfusion. SLC24A6 is associated with mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion. (PMID: 32728214, 20018762, 28219928)

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