SLC25A22 Recombinant antibody, PBS Only

SLC25A22 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 86163-1-PBS
Clone No.250788B11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

GC 1, GC1, GC-1, Glutamate/H(+) symporter 1, NET44

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

86163-1-PBS targets SLC25A22 in applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen SLC25A22 fusion protein Ag19958 Predict reactive species
Full Name solute carrier family 25 (mitochondrial carrier: glutamate), member 22
Calculated Molecular Weight 323 aa, 34 kDa
Observed Molecular Weight 30-34 kDa
GenBank Accession NumberBC023545
Gene Symbol SLC25A22
Gene ID (NCBI) 79751
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9H936
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

SLC25A22 encodes a mitochondrial glutamate/H+ symporter with highly expression in brain, especially in astrocytes, where it controls glutamate uptake. The mutations of SLC25A22 are associated with the early/infantile epileptic encephalopathies. It has been shown that SLC25A22 plays a key role in promoting proliferation and migration in cancer, such as human colorectal cancer (CRC) and Gallbladder cancer (GBC). And there is a result that the expression of SLC25A22 in GBC was significantly higher than that in adjacent tissues. 25402-1-AP antibody is specific to SLC25A22.(PMID: 30814911, 25033742, 24596948)

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