Product Information
22013-1-PBS targets SLC26A5 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag16631 Product name: Recombinant human SLC26A5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-86 aa of BC100832 Sequence: MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVS Predict reactive species |
| Full Name | solute carrier family 26, member 5 (prestin) |
| Calculated Molecular Weight | 744 aa, 81 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC100832 |
| Gene Symbol | SLC26A5 |
| Gene ID (NCBI) | 375611 |
| RRID | AB_3669384 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P58743 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
SLC26A5 (Prestin) is a protein that is housed in abundance within the lateral membrane of outer hair cells (OHC) in the organ of Corti. The protein imparts robust electromechanical activity to the cell that is unlike any other form of cellular motility, notably associated with a voltage-dependent, bell-shaped nonlinear capacitance (NLC) that reports on conformational changes in the protein (PMID: 32061780). SLC26A5 is responsible for acute sensitivity and frequency selectivity in the vertebrate auditory system (PMID: 34294052).
