SLC9A3R2 Polyclonal antibody

SLC9A3R2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 18891-1-AP

Synonyms

E3KARP, NHE3RF2, NHERF 2, NHERF2, OCTS2, SIP 1, SIP1, SLC9A3R2, SRY interacting protein 1, TKA 1

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Validation Data Gallery

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  WB analysis using 18891-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 18891-1-AP (SLC9A3R2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells, MCF-7 cells, T-47D cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

18891-1-AP targets SLC9A3R2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC9A3R2 fusion protein Ag13476
• Full Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
• Calculated Molecular Weight: 337 aa, 37 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC106001
• Gene Symbol: SLC9A3R2
• Gene ID (NCBI): 9351
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SLC9A3R2, also named as NHERF2, is a member of the Na+/H+ exchanger regulatory factor (NHERF) family of PDZ scaffolding proteins. SLC9A3R2 is needed for cGMP and carbachol-mediated inhibition as well as LPA and dexamethasone-mediated stimulation of NHE3. NHERF1 and NHERF2 are highly homologous structurally to each other but play different roles in the regulation of Na+ and Cl− transport.(PMID: 23612977)