SLC9A3R2 Polyclonal antibody, PBS Only

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• SLC9A3R2 Polyclonal antibody, PBS Only (18891-1-PBS)

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  WB analysis using 18891-1-AP (same clone as 18891-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18891-1-AP (SLC9A3R2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18891-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 18891-1-AP (same clone as 18891-1-PBS)

  WB result of SLC9A3R2 antibody (18891-1-AP; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC9A3R2 transfected MCF-7 cells. This data was developed using the same antibody clone with 18891-1-PBS in a different storage buffer formulation.

SLC9A3R2 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 18891-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

E3KARP, Na(+)/H(+) exchange regulatory cofactor NHE-RF2, NHE3RF2, NHERF 2, NHERF2

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Product Information

18891-1-PBS targets SLC9A3R2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag13476

  Product name: Recombinant human SLC9A3R2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-337 aa of BC106001

  Sequence: MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF

• Full Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
• Calculated Molecular Weight: 337 aa, 37 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC106001
• Gene Symbol: SLC9A3R2
• Gene ID (NCBI): 9351
• RRID: AB_3085570
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q15599
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SLC9A3R2, also named as NHERF2, is a member of the Na+/H+ exchanger regulatory factor (NHERF) family of PDZ scaffolding proteins. SLC9A3R2 is needed for cGMP and carbachol-mediated inhibition as well as LPA and dexamethasone-mediated stimulation of NHE3. NHERF1 and NHERF2 are highly homologous structurally to each other but play different roles in the regulation of Na+ and Cl− transport.(PMID: 23612977)