SLFN5 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 86424-1-RR (same clone as 86424-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86424-1-RR (SLFN5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86424-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 86424-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86424-1-RR against Human SLFN5 were performed. The affinity constant is below 1 pM.

SLFN5 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86424-1-PBS

Clone No.251214D8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Schlafen family member 5

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Product Information

86424-1-PBS targets SLFN5 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag9959

  Product name: Recombinant human SLFN5 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-338 aa of BC021238

  Sequence: MSLRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPG

• Full Name: schlafen family member 5
• Calculated Molecular Weight: 338 aa, 38 kDa
• Observed Molecular Weight: 90-100 kDa
• GenBank Accession Number: BC021238
• Gene Symbol: SLFN5
• Gene ID (NCBI): 162394
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q08AF3
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Schlafen family member 5 (SLFN5) is a member of the Schlafen family of proteins, a group of type 1 IFN-inducible proteins. In addition to an AAA (ATPase) domain and a specific SLFN box, the SLFN5 gene contains a helicase domain as well as a nuclear localization sequence, which suggests a role for this protein in transcription-related processes. A growing number of findings suggest that human Schlafen family member 5(SLFN5) plays a key role in malignancy.