SLX4 Polyclonal antibody

SLX4 Polyclonal Antibody for WB, ELISA

Cat No. 31867-1-AP

Reviews (1)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

BTBD12, BTB (POZ) domain containing 12, KIAA1784, KIAA1987

Formulation: PBS, Azide, Glycerol

PBS, Azide, Glycerol

Conjugate: Unconjugated

Unconjugated

Size/Concentration:

SKU:

-/ -

Freight/Packing: -

Quantity

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WB analysis using 31867-1-AP
Various lysates were subjected to SDS PAGE followed by western blot with 31867-1-AP (SLX4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Overview

Tested Applications
Product Information
Protocols
Reviews (1)

Print datasheet

MSDS SDS

Tested Applications

Positive WB detected in

DU 145 cells, HeLa cells, mouse testis tissue, rat testis tissue

Recommended dilution

Application	Dilution
Western Blot (WB)	WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

31867-1-AP targets SLX4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity	human, mouse, rat
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag36095 Product name: Recombinant human BTBD12 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1530-1834 aa of BC036335 Sequence: MPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGEVSASQAAVQAADTDEALRCYIRSKPALYQKVLLYQPFELRELQAELRQNGLRVSSRRLLDFLDTHCITFTTAATRREKLQGRRRQPRGKKKVERN Predict reactive species
Full Name	BTB (POZ) domain containing 12
Calculated Molecular Weight	1834 aa, 200 kDa
Observed Molecular Weight	180-200 kDa
GenBank Accession Number	BC036335
Gene Symbol	BTBD12
Gene ID (NCBI)	84464
RRID	AB_3742487
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity Purification
UNIPROT ID	Q8IY92
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SLX4 (Structure-specific endonuclease subunit SLX4) is a scaffold protein that assembles multiple structure-specific nucleases, including SLX1, MUS81-EME1, and XPF-ERCC1. These nucleases are essential for resolving complex DNA structures that arise during DNA replication, repair, and recombination (PMID: 34804132). SLX4 is a key protein involved in DNA repair and genome stability, with significant implications for genetic disorders and cancer.