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SNIP/p140Cap Polyclonal antibody, PBS Only

SNIP/p140Cap Polyclonal Antibody for WB, Indirect ELISA

Cat No. 29890-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

29890-1-PBS targets SNIP/p140Cap in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag31857

Product name: Recombinant human SNIP protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1011-1182 aa of

Sequence: RSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARNSSIS

Predict reactive species
Full Name SNAP25-interacting protein
Calculated Molecular Weight127 kDa
Observed Molecular Weight145 kDa
Gene Symbol SNIP
Gene ID (NCBI) 80725
RRIDAB_3086180
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9C0H9
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

SNIP, also named SRC kinase signaling inhibitor 1 (SRCIN1) and p140 Cas-associated protein (p140CAP), contains two regions of highly charged amino acids, two proline-rich regions, and two coiled-coil domains. SNIP plays a role in SRC inactivation and acts as a tumor suppressor gene in cancers. MiR-32 suppresses the expression of SNIP, thereby suppressing proliferation and epithelial-mesenchymal transition (EMT) of human liver cancer cells (PMID: 28550679).

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