SNRNP25 Polyclonal antibody, PBS Only

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• SNRNP25 Polyclonal antibody, PBS Only (19890-1-PBS)

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  IHC staining of mouse cerebellum using 19890-1-AP (same clone as 19890-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 19890-1-AP (SNRNP25 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19890-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 19890-1-AP (same clone as 19890-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 19890-1-AP (SNRNP25 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19890-1-PBS in a different storage buffer formulation.

SNRNP25 Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 19890-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

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Product Information

19890-1-PBS targets SNRNP25 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag13724

  Product name: Recombinant human SNRNP25 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-132 aa of BC001381

  Sequence: MDVFQEGLAMVVQDPLLCDLPIQVTLEEVNSQIALEYGQAMTVRVCKMDGEVMPVVVVQSATVLDLKKAIQRYVQLKQEREGGIQHISWSYVWRTYHLTSAGEKLTEDRKKLRDYGIRNRDEVSFIKKLRQK

• Full Name: small nuclear ribonucleoprotein 25kDa (U11/U12)
• Calculated Molecular Weight: 132 aa, 15 kDa
• GenBank Accession Number: BC001381
• Gene Symbol: SNRNP25
• Gene ID (NCBI): 79622
• RRID: AB_3085590
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9BV90
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SNRNP25, small nuclear ribonucleoprotein U11/U12 subunit 25, encodes a 25K protein that is a component of the U12-type spliceosome. Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. LRP1-SNRNP25 fusion gene promotes osteosarcoma cell invasion and migration (PMID: 26738504, PMID: 25300797).