SNX15 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 85909-3-RR (same clone as 85909-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85909-3-RR (SNX15 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85909-3-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 85909-3-RR

  Biolayer interferometry (BLl) kinetic assays of 85909-3-RR against Human SNX15 were performed. The affinity constant is 11.9 pM.

SNX15 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85909-3-PBS

Clone No.250152G10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

HSAF001435, sorting nexin 15, Sorting nexin-15

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Product Information

85909-3-PBS targets SNX15 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag9006

  Product name: Recombinant human SNX15 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-342 aa of BC009897

  Sequence: MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP

• Full Name: sorting nexin 15
• Calculated Molecular Weight: 342 aa, 38 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC009897
• Gene Symbol: SNX15
• Gene ID (NCBI): 29907
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9NRS6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SNX15 belongs to the sorting nexin family and is involved in several stages of intracellular trafficking. Overexpression of SNX15 results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits (PMID: 11085978). SNX15 is widely expressed, with the highest expression in skeletal muscle, heart, brain, kidney, spleen, thymus, and small intestine.