SORBS2 Recombinant antibody, PBS Only

SORBS2 {ptg:Brand} Recombinant Antibody for WB, IF/ICC, FC (Intra), ELISA
Cat No. 83189-3-PBS
Clone No.240023A8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, FC (Intra), ELISA

Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg-binding protein 2, Arg/Abl-interacting protein 2, 240023A8

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

83189-3-PBS targets SORBS2 in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen SORBS2 fusion protein Ag20041 Predict reactive species
Full Name sorbin and SH3 domain containing 2
Calculated Molecular Weight 1100 aa, 124 kDa
Observed Molecular Weight 70-75 kDa
GenBank Accession NumberBC011883
Gene Symbol SORBS2
Gene ID (NCBI) 8470
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO94875
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

SORBS2, also known as ARGBP2, has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. SORBS2 is widely expressed in human tissues and extremely abundant in the heart. In epithelial cells SORBS2 is located in stress fibers and the nucleus; In cardiac muscle cells. SORBS2 is located in the Z-disks of sarcomeres. The subcellular localization suggests that SORBS2 functions as an adapter protein to assemble signaling complexes in stress fibers, and may influence the contractile or elastic properties of cardiac sarcomeres(PMID: 9211900). Alternate splicing results in multiple transcript variants( PMID: 28961272).

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