SSBP1 Recombinant antibody, PBS Only

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  WB analysis using 84939-3-RR (same clone as 84939-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84939-3-RR (SSBP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84939-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84939-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84939-3-RR against Human SSBP1 were performed. The affinity constant is 0.144 nM.

SSBP1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84939-3-PBS

Clone No.242519C5

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

242519C5, Mt SSB, MtSSB, Mt-SSB, PWP1 interacting protein 17

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Product Information

84939-3-PBS targets SSBP1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: SSBP1 fusion protein Ag2860
• Full Name: single-stranded DNA binding protein 1
• Calculated Molecular Weight: 148 aa, 17 kDa
• Observed Molecular Weight: 17 kDa
• GenBank Accession Number: BC000895
• Gene Symbol: SSBP1
• Gene ID (NCBI): 6742
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q04837
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SSBP1 is a housekeeping gene involved in mitochondrial biogenesis. it binds preferentially and cooperatively to ss-DNA in the maintainance of genome stability. SSBP1 acted as a homotetramer to stabilize the displaced single strand of the normal and expanded displacement loop (D loop) during mtDNA replication, thus preventing formation of secondary single-stranded DNA structures, which could stop the gamma-DNA polymerase.