|Positive WB detected in||mouse skeletal muscle tissue, HeLa cells, A549 cells|
|Positive IP detected in||A549 cells|
|Positive IHC detected in||human colon cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
11842-1-AP targets STBD1 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||mouse, rat, chicken|
|Host / Isotype||Rabbit / IgG|
|Immunogen||STBD1 fusion protein Ag2481|
|Full Name||starch binding domain 1|
|Calculated molecular weight||41 kDa|
|Observed molecular weight||35-43 kDa|
|GenBank accession number||BC022301|
|Gene ID (NCBI)||8987|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
STBD1 may have the capability to bind to carbohydrates. It functions as a glycogen receptor that tethers glycogen to autophagic membranes for delivery and breakdown in lysosomes. STBD1 appears molecular mass of 35-38 kDa band in mouse/rat tissues and 38-43 kDa in human tissue.
Glycogen accumulation and phase separation drives liver tumor initiation.
Acta Pharmacol Sin
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism.
J Cell Sci
Stbd1 promotes glycogen clustering during endoplasmic reticulum stress and supports survival of mouse myoblasts
Transgenic muscle specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism and endurance.
J Cell Sci
Mouse Stbd1 is N-myristoylated and affects ER-mitochondria association and mitochondrial morphology.
J Biol Chem
Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.