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  • KD/KO Validated

STRN Polyclonal antibody

STRN Polyclonal Antibody for FC, IF, IHC, IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, IHC, IF, FC, ELISA

Conjugate

Unconjugated

Cat no : 21624-1-AP

Synonyms

SG2NA, Striatin, STRN



Tested Applications

Positive WB detected inA549 cells, rat brain tissue, NIH/3T3 cells, mouse brain tissue, HEK-293T cells, HeLa cells, Jurkat cells
Positive IP detected inmouse brain tissue
Positive IHC detected inmouse brain tissue, human liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHela cells
Positive FC detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:10-1:100
Flow Cytometry (FC)FC : 0.40 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

21624-1-AP targets STRN in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen STRN fusion protein Ag15984
Full Name striatin, calmodulin binding protein
Calculated molecular weight 780 aa, 86 kDa
Observed molecular weight 110 kDa
GenBank accession numberBC106879
Gene symbol STRN
Gene ID (NCBI) 6801
RRIDAB_10863122
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

STRN (Striatin), a 780-amino acid protein, was identified and cloned more than a decade ago. In adult mammals, striatin is mainly expressed in neurons of both the central and peripheral nervous systems with very high levels of expression in the striatum, hence its name. STRN-ALK fusion may be a potential therapeutic target in the aggressive forms of thyroid cancer (PMID: 24475247).

Protocols

Product Specific Protocols
WB protocol for STRN antibody 21624-1-APDownload protocol
IHC protocol for STRN antibody 21624-1-APDownload protocol
IF protocol for STRN antibody 21624-1-APDownload protocol
IP protocol for STRN antibody 21624-1-APDownload protocol
FC protocol for STRN antibody 21624-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB,IF

Front Cell Dev Biol

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses.

Authors - Prathamesh T Nadar-Ponniah
  • KO Validated
humanWB

J Biol Chem

Heavy Metal-Induced Metallothionein Expression is Regulated by Specific Protein Phosphatase 2A Complexes.

Authors - Liping Chen
ratWB

Sci Rep

Precise and systematic survey of the efficacy of multicomponent drugs against functional dyspepsia.

Authors - Junying Wei
humanWB,IHC

Biomed Res Int

High STRN Expression Promotes HCC Invasion and Migration but Not Cell Proliferation or Apoptosis through Facilitating Epithelial-Mesenchymal Transition.

Authors - Qian-Yu Du
  • KD Validated
ratWB

Genes (Basel)

Effect of Combined Methamphetamine and Oxycodone Use on the Synaptic Proteome in an In Vitro Model of Polysubstance Use

Authors - Daniel Meyer
human,mouseWB

Kaohsiung J Med Sci

CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR-199b-5p and regulating STRN expression

Authors - Jing Liu

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Vicki (Verified Customer) (02-21-2022)

Great antibody for cell lysates

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: Primary rat neurons