STX1A Polyclonal antibody

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• STX1A Polyclonal antibody (55164-1-AP)

STX1A Polyclonal Antibody for WB, ELISA

Cat No. 55164-1-AP Copied!

Publications (1)

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

syntaxin 1A (brain), Syntaxin 1A, STX1, p35 1, Neuron specific antigen HPC 1

• 

  WB analysis of human plasma using 55164-1-AP

  human plasma was subjected to SDS PAGE followed by western blot with 55164-1-AP (STX1A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: human plasma

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

55164-1-AP targets STX1A in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: syntaxin 1A (brain)
• Calculated Molecular Weight: 33 kDa
• Observed Molecular Weight: 35 kDa
• GenBank Accession Number: NM_004603
• Gene Symbol: STX1A
• Gene ID (NCBI): 6804
• RRID: AB_3086433
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q16623
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Syntaxins are a family of transmembrane proteins that belong to the SNARE complex (PMID: 11737951). In conjunction with other SNAREs and with the cytoplasmic NSF and SNAP proteins, syntaxins mediate vesicle fusion in diverse vesicular transport processes along the exocytic and endocytic pathways (PMID: 11737951). Syntaxin 1A (STX1A) and 1B (STX1B), two closely related isoforms of syntaxin 1, are involved in synaptic vesicle docking and fusion during neurotransmitter release (PMID: 7690687; 1321498; 18691641). Syntaxin 1A is associated with a variety of neurological diseases, including epilepsy, attention deficit hyperactivity disorder (ADHD), migraine, etc (PMID: 26918652; 25445064; 22250207). This antibody recognizes human STX1A.

Publications

What published studies show

The STX1A Polyclonal antibody (Cat# 55164-1-AP) has 1 total citation. The cited publication appeared in Advanced Science (Impact Factor 14.1) and investigated human brain-derived extracellular vesicles and their effects on synaptic activity using an air-liquid microfluidic platform. The research field is neuroscience, specifically synaptic biology and extracellular vesicle function. The antibody was applied in Western Blot (WB) with human samples.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Adv Sci (Weinh); Assessing the Nature of Human Brain-Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air-liquid Microfluidic Platform.; Authors - Corentin Bernou