Product Information
55164-1-PBS targets STX1A in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | syntaxin 1A (brain) |
| Calculated Molecular Weight | 33 kDa |
| Observed Molecular Weight | 35 kDa |
| GenBank Accession Number | NM_004603 |
| Gene Symbol | STX1A |
| Gene ID (NCBI) | 6804 |
| RRID | AB_3086433 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q16623 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Syntaxins are a family of transmembrane proteins that belong to the SNARE complex (PMID: 11737951). In conjunction with other SNAREs and with the cytoplasmic NSF and SNAP proteins, syntaxins mediate vesicle fusion in diverse vesicular transport processes along the exocytic and endocytic pathways (PMID: 11737951). Syntaxin 1A (STX1A) and 1B (STX1B), two closely related isoforms of syntaxin 1, are involved in synaptic vesicle docking and fusion during neurotransmitter release (PMID: 7690687; 1321498; 18691641). Syntaxin 1A is associated with a variety of neurological diseases, including epilepsy, attention deficit hyperactivity disorder (ADHD), migraine, etc (PMID: 26918652; 25445064; 22250207). This antibody recognizes human STX1A.
