SYTL4 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12128-1-AP

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Con: 39 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Transfected HEK-293 cells

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
synaptotagmin-like 4

Calculated molecular weight:
671aa,76 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SYTL4

Synonyms
DKFZp451P0116, Exophilin 2, FLJ40960, Granuphilin, SLP4, synaptotagmin like 4, Synaptotagmin like protein 4, SYTL4
Background

SYTL4, also known as SLP4 or granuphilin, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL4 is specifically expressed on dense-core granules in certain neuroendocrine cells and negatively controls dense-core vesicle exocytosis through specific interaction with Rab27A. (PMID: 16481396; 16473610)


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