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SYTL4 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12128-1-AP

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Con: 39 μg/150 μl

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Tested Applications
Applications:
ELISA, IHC, WB
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12128-1-AP;Transfected HEK-293 cells

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 12128-1-AP( SYTL4 Antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours

12128-1-AP;human breast cancer tissue

Immunohistochemical of paraffin-embedded human breast cancer using 12128-1-AP(SYTL4 antibody) at dilution of 1:50 (under 10x lens)

Species specificity:
human, mouse, rat
Positive WB detected in:
Transfected HEK-293 cells
Positive IHC detected in:
human breast cancer tissue
Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
SYTL4 fusion protein ag2772
Full name:
synaptotagmin-like 4
Calculated molecular weight:
671aa,76 kDa
Observed molecular weight:
GenBank accession number:
BC014913
Gene ID (NCBI):
94121
Gene symbol
SYTL4
Synonyms
DKFZp451P0116, Exophilin 2, FLJ40960, Granuphilin, SLP4, synaptotagmin like 4, Synaptotagmin like protein 4, SYTL4
Background

SYTL4, also known as SLP4 or granuphilin, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL4 is specifically expressed on dense-core granules in certain neuroendocrine cells and negatively controls dense-core vesicle exocytosis through specific interaction with Rab27A. (PMID: 16481396; 16473610)


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