Siglec-15 Polyclonal antibody
Siglec-15 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Cat no : 28594-1-AP
|Positive WB detected in||PC-3 cells, U-87 MG cells|
|Western Blot (WB)||WB : 1:1000-1:5000|
|Sample-dependent, check data in validation data gallery|
28594-1-AP targets Siglec-15 in WB, ELISA applications and shows reactivity with Human samples.
|Host / Isotype||Rabbit / IgG|
|Immunogen||Siglec-15 fusion protein Ag29829|
|Full Name||sialic acid binding Ig-like lectin 15|
|Calculated molecular weight||36 kDa|
|Observed molecular weight||38-40 kDa|
|GenBank accession number||NM_213602|
|Gene ID (NCBI)||284266|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Sialic acid binding Ig-like lectin 15 (Siglec-15) is a member of the Siglec family of glycan-recognition proteins. Siglec-15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain, and a short cytoplasmic tail (PMID: 17483134). It is mainly expressed on a subset of myeloid lineage cells and can be upregulated in many cancers (PMID: 32939323). Siglec-15 has been reported as a immune suppressor and a potential target for normalization cancer immunotherapy (PMID: 30833750). Siglec-15 has a calculated molecular weight of 36 kDa. It has been detected at 38-40 kDa due to glycosylation (PMID: 32921411).
|Product Specific Protocols|
|WB protocol for Siglec-15 antibody 28594-1-AP||Download protocol|
|Click here to view our Standard Protocols|
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Rebecca (Verified Customer) (07-21-2022)
Positive staining identified at 1:500 dilution in patient FFPE tissue. Slight background.