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Anti-Human TCR Vγ9Vδ2 Rabbit Recombinant Antibody, PBS Only (98526-1-PBS)

Anti-Human TCR Vγ9Vδ2 Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human TCR Vγ9Vδ2 Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98526-1-PBS-1MG

TCR Vγ9Vδ2 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98526-1-PBS

Clone No. 251678A1

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

TCR gamma delta, Vγ9Vδ2

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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Filter: AllFC

FC experiment of human PBMCs using 98526-1-RR (same clone as 98526-1-PBS)
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
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1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.
FC experiment of human PBMCs using 98526-1-RR (same clone as 98526-1-PBS)
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

98526-1-PBS targets TCR Vγ9Vδ2 in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	Recombinant protein Predict reactive species
Full Name	TCR Vγ9Vδ2
Gene Symbol
Gene ID (NCBI)
RRID	AB_3746154
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

TCR Vγ9Vδ2 refers to a specific type of T cell receptor (TCR) found on a subset of gamma delta (γδ) T cells called Vγ9Vδ2 T cells. These cells are a major population of human γδ T cells in the blood and are characterized by the expression of a unique TCR that recognizes phosphoantigens (pAg). Vγ9Vδ2 T cell activation is tightly regulated by a variety of activating or inhibitory receptors which are specific for constitutively expressed or stress-modulated ligands (PMID: 20447835, 40040716). The most effective TCR Vg9Vd2-mediated cell activation relies on TCR interaction with BTN3A1, BTN3A2, and BTN2A1 molecules expressed by target cells (PMID: 25566259).