TCTN2 Recombinant antibody

TCTN2 Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


Human, rat







Cat no : 82121-1-RR


C12orf38, FLJ12975, TCTN2, TECT2, Tectonic 2, tectonic family member 2

Tested Applications

Positive WB detected inHEK-293 cells, A431 cells, HeLa cells, Jurkat cells, K-562 cells, RAW 264.7 cells

Recommended dilution

Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

82121-1-RR targets TCTN2 in WB, ELISA applications and shows reactivity with Human, rat samples.

Tested Reactivity Human, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TCTN2 fusion protein Ag10725
Full Name tectonic family member 2
Calculated Molecular Weight 697 aa, 77 kDa
Observed Molecular Weight90 kDa
GenBank Accession NumberBC009112
Gene Symbol TCTN2
Gene ID (NCBI) 79867
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TCTN2 (tectonic-2 or TECT2) is a type I membrane protein that belongs to the tectonic family, which consists of TCTN1, TCTN2 and TCTN3. Studies in mice suggest that tectonic may be involved in Hedgehog (Hh) signaling, and essential for ciliogenesis. Tectonic is component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. It exists two spilcing isoforms. The first aberrant transcript introduces 104 base pair from intron 13 and would delete 196 original amino acid, introduce two novel amino acids, and prematurely truncate the 697aa protein at residue number 504. The second transcript lacks exon 14 and would delete 195 original amino acids, introduce four novel amino acids, and prematurely truncate the 697 aa protein at residue number 507. The molecular weight of two isoforms are about 50kDa. We detected the 50kDa and 90kDa protein by immunoprecipitaion, but 50kDa protein may be the splicing isoform or non-specific band.


Product Specific Protocols
WB protocol for TCTN2 antibody 82121-1-RRDownload protocol
Standard Protocols
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