TEX11 Polyclonal antibody

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• KD/KO Validated

TEX11 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 17266-1-AP

Synonyms

testis expressed 11, TEX11, TGC1, TSGA3

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Validation Data Gallery

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  WB analysis using 17266-1-AP

  LNCaP cells lysates were subjected to SDS PAGE followed by western blot with 17266-1-AP (TEX11 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of DU 145 using 17266-1-AP

  WB result of TEX11 antibody (17266-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-TEX11 transfected DU 145 cells.

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Tested Applications

• Positive WB detected in: LNCaP cells, DU 145 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IHC: See 1 publications below

Product Information

17266-1-AP targets TEX11 in WB, IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TEX11 fusion protein Ag11012
• Full Name: testis expressed 11
• Calculated Molecular Weight: 925 aa, 107 kDa
• Observed Molecular Weight: 66-72 kDa
• GenBank Accession Number: BC036016
• Gene Symbol: TEX11
• Gene ID (NCBI): 56159
• RRID: AB_2201874
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Testis-expressed 11 (TEX11) is an X-chromosome-encoded germ-cell-specific protein that is expressed most abundantly in spermatogonia and early spermatocytes in the testes. The TEX11 protein was found to form discrete foci along the synaptonemal complexes (SCs) on meiotic chromosomes and was shown to be essential for meiosis in males.

Publications

Species	Application	Title
human	WB,IHC	Oncogene; Downregulation of TEX11 promotes S-Phase progression and proliferation in colorectal cancer cells through the FOXO3a/COP1/c-Jun/p21 axis; Authors - Xiaodong Zhang