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TFPT Polyclonal antibody, PBS Only

TFPT Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 10097-2-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

TCF3 fusion partner, Protein FB1, INO80F, INO80 complex subunit F, FB1

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

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Quantity

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Product Information

10097-2-PBS targets TFPT in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag0131

Product name: Recombinant human TFPT protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 39-253 aa of BC001728

Sequence: SELETEVEFVSGGLGGSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDKLLPYPTLASPAS

Predict reactive species
Full Name TCF3 (E2A) fusion partner (in childhood Leukemia)
Calculated Molecular Weight 29 kDa
Observed Molecular Weight 29 kDa
GenBank Accession NumberBC001728
Gene Symbol TFPT
Gene ID (NCBI) 29844
RRIDAB_2240572
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDP0C1Z6
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

TFPT/FB1 is one of three fusion partners of the E2A gene. TFPT/FB1 is expressed at low level in a variety of human tissues, including hemopoietic cell lines from different lineages. The function of the putative TFPT/FB1 protein, however, is currently unknown as database sequence comparisons have failed to reveal strong homology with known proteins. The E2A-TFPT/FB1 fusion appears to be a recurrent feature of pre-B ALLs, suggesting that it might have a role in the development and/or progression of leukemogenesis. The gene encoding TFPT/FB1 is localized on 19q13.4.

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