TGFB1I1 Recombinant antibody, PBS Only

• 

  WB analysis of HeLa using 85859-5-RR (same clone as 85859-5-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 85859-5-RR (TGFB1I1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85859-5-PBS in a different storage buffer formulation.

• 

  WB analysis of SKOV-3 using 85859-5-RR (same clone as 85859-5-PBS)

  SKOV-3 cells were subjected to SDS PAGE followed by western blot with 85859-5-RR (TGFB1I1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85859-5-PBS in a different storage buffer formulation.

• 

  WB analysis of rat colon using 85859-5-RR (same clone as 85859-5-PBS)

  rat colon tissue were subjected to SDS PAGE followed by western blot with 85859-5-RR (TGFB1I1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85859-5-PBS in a different storage buffer formulation.

TGFB1I1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85859-5-PBS

Clone No.250139E8

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Indirect ELISA

Synonyms

HIC5, Androgen receptor-associated protein of 55 kDa, ARA55, Hic-5, Hydrogen peroxide-inducible clone 5 protein

---

Product Information

85859-5-PBS targets TGFB1I1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: TGFB1I1 fusion protein Ag0868
• Full Name: transforming growth factor beta 1 induced transcript 1
• Calculated Molecular Weight: 48 kDa
• Observed Molecular Weight: 48-50 kDa
• GenBank Accession Number: BC001830
• Gene Symbol: HIC5
• Gene ID (NCBI): 7041
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O43294
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

HIC5 (Hydrogen Peroxide-Inducible Clone 5), also known as TGFB1I1, ARA55, or TSC-5. It was first identified in 1994 as a gene induced by transforming growth factor-β (TGF-β) or hydrogen peroxide (PMID: 36222304). HIC5 is a member of the Paxillin protein family and functions as a molecular adapter, delivering signals when the cellular adhesion environment changes. Given its role in cancer and fibrotic diseases, HIC5 is a potential therapeutic target. For example, targeting HIC5 or the GR tau2 region could modulate the set of genes regulated by GR, providing opportunities for intervention (PMID: 24591583).