CoraLite® Plus 647-conjugated TMEM119 Monoclonal antibody

TMEM119 Monoclonal Antibody for

Host / Isotype

Mouse / IgG3

Reactivity

Human, Pig, Mouse, Rat

Applications

IF, FC

Conjugate

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

1E7A2

Cat no : CL647-66948

Synonyms

TMEM119, transmembrane protein 119, UNQ731/PRO1415



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL647-66948 targets TMEM119 in IF, FC applications and shows reactivity with Human, Pig, Mouse, Rat samples.

Tested Reactivity Human, Pig, Mouse, Rat
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Immunogen TMEM119 fusion protein Ag26286
Full Name transmembrane protein 119
Calculated Molecular Weight 29 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberNM_181724
Gene Symbol TMEM119
Gene ID (NCBI) 338773
Conjugate CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission Maxima Wavelengths654 nm / 674 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TMEM119 immunohistochemistry might provide a useful tool for investigating the biology and pathology of human microglia(PMID: 26250788). Microglia can be detected clearly using Catalog#66948-1-Ig. The predicted MW of TMEM119 is 29 kDa. Catalog#66948-1-Ig recognizes 50 kDa band may due to glycosylation.

Publications

SpeciesApplicationTitle
IF,FC

J Neuroinflammation

Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model

Authors - A D Roseborough