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CoraLite® Plus 647-conjugated TMEM119 Monoclonal antibody

TMEM119 Monoclonal Antibody for
Cat No. CL647-66948
Clone No.1E7A2

Host / Isotype

Mouse / IgG3

Reactivity

Human, Pig, Mouse, Rat

Applications

IF, FC

TMEM119, transmembrane protein 119, UNQ731/PRO1415

Formulation:  PBS, Proclin 300, BSA, Glycerol
PBS, Proclin 300, BSA, Glycerol
Conjugate:  CoraLite® Plus 647
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

CL647-66948 targets TMEM119 in IF, FC applications and shows reactivity with Human, Pig, Mouse, Rat samples.

Tested Reactivity Human, Pig, Mouse, Rat
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Immunogen

CatNo: Ag26286

Product name: Recombinant human TMEM119 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 119-218 aa of NM_181724

Sequence: MRQKQKASAYYPSSFPKKKYVDQSDRAGGPRAFSEVPDRAPDSRPEEALDSSRQLQADILAATQNLKSPTRAALGGGDGARMVEGRGAEEEEKGSQEGDQE

Predict reactive species
Full Name transmembrane protein 119
Calculated Molecular Weight 29 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberNM_181724
Gene Symbol TMEM119
Gene ID (NCBI) 338773
Conjugate CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission Maxima Wavelengths654 nm / 674 nm
FormLiquid
Purification MethodProtein A purification
UNIPROT IDQ4V9L6
Storage Buffer PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TMEM119 immunohistochemistry might provide a useful tool for investigating the biology and pathology of human microglia(PMID: 26250788). Microglia can be detected clearly using Catalog#66948-1-Ig. The predicted MW of TMEM119 is 29 kDa. Catalog#66948-1-Ig recognizes 50 kDa band may due to glycosylation.

Publications

SpeciesApplicationTitle
IF,FC

J Neuroinflammation

Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model

Authors - A D Roseborough
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