TMEM231 Polyclonal antibody, PBS Only

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• TMEM231 Polyclonal antibody, PBS Only (23731-1-PBS)

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  IHC staining of human pancreas using 23731-1-AP (same clone as 23731-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas slide using 23731-1-AP (TMEM231 Antibody) at dilution of 1:50. (under 10x lens). This data was developed using the same antibody clone with 23731-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 23731-1-AP (same clone as 23731-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas slide using 23731-1-AP (TMEM231 Antibody) at dilution of 1:50. (under 40x lens). This data was developed using the same antibody clone with 23731-1-PBS in a different storage buffer formulation.

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  IF Staining of MDCK using 23731-1-AP (same clone as 23731-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MDCK cells using TMEM231 antibody (23731-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23731-1-PBS in a different storage buffer formulation.

TMEM231 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Cat No. 23731-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, canine

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

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Product Information

23731-1-PBS targets TMEM231 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, canine samples.

• Tested Reactivity: human, canine
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag20669

  Product name: Recombinant human TMEM231 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 47-316 aa of BC010609

  Sequence: GFWLKRSSYEEQPTVRFQHQVLLVALLGPESDGFLAWSTFPAFNRLQGDRLRVPLVSTREEDRNQDGKTDMLHFKLELPLQSTEHVLGVQLILTFSYRLHRMATLVMQSMAFLQSSFPVPGSQLYVNGDLRLQQKQPLSCGGLDARYNISVINGTSPFAYDYDLTHIVAAYQERNVTTVLNDPNPIWLVGRAADAPFVINAIIRYPVEVISYQPGFWEMVKFAWVQYVSILLIFLWVFERIKIFVFQNQVVTTIPVTVTPRGDLCKEHLS

• Full Name: hypothetical protein FLJ22167
• Calculated Molecular Weight: 345 aa, 39 kDa
• GenBank Accession Number: BC010609
• Gene Symbol: TMEM231
• Gene ID (NCBI): 79583
• RRID: AB_2879312
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H6L2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Transmembrane protein 231 (TMEM231) encodes a 36 kDa two-pass transmembrane protein that is part of the B9 complex and localizes to the base of the ciliary axoneme at the TZ. TMEM231 was first identified as a causative gene for MKS and participates in the formation of the diffusion barrier between the cilia and plasma membrane (PMID: 34912761, 37736303). Tmem231 mutant mice have developmental defects reminiscent of MKS patients, including corticomedullary kidney cysts, polydactyly and hepatic ductal plate malformation (PMID: 25869670).