TRIM61 Polyclonal antibody, PBS Only

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• TRIM61 Polyclonal antibody, PBS Only (24371-1-PBS)

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  IHC staining of mouse liver using 24371-1-AP (same clone as 24371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 24371-1-AP (TRIM61 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24371-1-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 24371-1-AP (same clone as 24371-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TRIM61 antibody (24371-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 24371-1-PBS in a different storage buffer formulation.

TRIM61 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Cat No. 24371-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

tripartite motif containing 61, TRIM, RNF35, RING finger protein 35

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Product Information

24371-1-PBS targets TRIM61 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag21656

  Product name: Recombinant human TRIM61 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 176-209 aa of BC089393

  Sequence: MESPSVTRLECSCTISAHFNLRLPGSSDSSASGS

• Full Name: tripartite motif-containing 61
• Calculated Molecular Weight: 209 aa, 24 kDa
• GenBank Accession Number: BC089393
• Gene Symbol: TRIM61
• Gene ID (NCBI): 391712
• RRID: AB_3669434
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q5EBN2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TRIM61 is a member of the tripartite motif (TRIM) protein family. The RING domain in TRIM proteins, including TRIM61, can mediate the conjugation of proteins with ubiquitin, small ubiquitin-like modifier (SUMO), or the ubiquitin-like molecule IFN-stimulated protein of 15 kDa (ISG15), contributing to the biological flexibility of TRIM proteins. The E3 ligase activity of TRIM proteins, such as TRIM61, is essential for their role in post-translational modification, which plays a crucial role in cellular processes often resulting in targeted degradation of conjugated proteins.