TRIM63 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 82345-4-RR (same clone as 82345-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82345-4-RR (TRIM63 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82345-4-PBS in a different storage buffer formulation.

TRIM63 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 82345-4-PBS

Clone No.242055A4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

MuRF1, MuRF 1, Iris RING finger protein, IRF, EC:2.3.2.27

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Product Information

82345-4-PBS targets TRIM63 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: tripartite motif-containing 63
• Calculated Molecular Weight: 40 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: NM_032588
• Gene Symbol: TRIM63
• Gene ID (NCBI): 84676
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q969Q1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TRIM63, also named as IRF, MURF1, RNF28 and SMRZ, is E3 ubiquitin ligase. It is regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. TRIM63 may play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. It may regulate the organization of myofibrils through TTN in muscle cells. TRIM63 is in muscle-specific expression.