TRIML2 Polyclonal antibody, PBS Only

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• TRIML2 Polyclonal antibody, PBS Only (31976-1-PBS)

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  WB analysis using 31976-1-AP (same clone as 31976-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31976-1-AP (TRIML2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31976-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 31976-1-AP (same clone as 31976-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31976-1-AP (TRIML2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31976-1-PBS in a different storage buffer formulation.

TRIML2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 31976-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

EC:2.3.2.27, Probable E3 ubiquitin-protein ligase TRIML2, RING-type E3 ubiquitin transferase TRIML2, SPRY domain-containing protein 6, SPRYD6

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Product Information

31976-1-PBS targets TRIML2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag37106

  Product name: Recombinant human TRIML2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-155 aa of BC111959

  Sequence: MVCGIQEAAENYRKLFQEILNTSREKLEAAKSILTDEQERMAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLAL

• Full Name: tripartite motif family-like 2
• Calculated Molecular Weight: 50 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC111959
• Gene Symbol: TRIML2
• Gene ID (NCBI): 205860
• RRID: AB_3670164
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q8N7C3
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Tripartite motif family like 2 (TRIML2, also known as SPRYD6) is a member of the tripartite motif (TRIM) family of proteins. It probably interacts with p53 to facilitate the modification of p53 with small ubiquitin-like modifier 2 (SUMO2) (PMID: 25256710). By regulating p53, TRIML2 may also be an important factor in the pathogenesis of Alzheimer's disease (PMID: 27471163).