TSPAN10 Polyclonal antibody, PBS Only

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• TSPAN10 Polyclonal antibody, PBS Only (14430-1-PBS)

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  WB analysis of hTERT-RPE1 using 14430-1-AP (same clone as 14430-1-PBS)

  WB result of TSPAN10 antibody (14430-1-AP; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-TSPAN10 transfected hTERT-RPE1 cells. This data was developed using the same antibody clone with 14430-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 cells using 14430-1-AP (same clone as 14430-1-PBS)

  IF result (nuclear and the base of cilia stain) of anti-TSPAN10 (14430-1-AP, 1:50) with human hTERT-RPE1 (MeOH fixation) cells by Dr. Moshe Kim. This data was developed using the same antibody clone with 14430-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

TSPAN10 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 14430-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

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Product Information

14430-1-PBS targets TSPAN10 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag5807

  Product name: Recombinant human TSPAN10 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 181-355 aa of BC032802

  Sequence: SLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAARSGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG

• Full Name: tetraspanin 10
• Calculated Molecular Weight: 36.5 kDa
• Observed Molecular Weight: 36-40 kDa
• GenBank Accession Number: BC032802
• Gene Symbol: TSPAN10
• Gene ID (NCBI): 83882
• RRID: AB_2878057
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H1Z9
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TSPAN10 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN10 belongs to the TSPANC8 subfamily, which also include TSPAN5, TSPAN14, TSPAN15, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).