Product Information
27617-1-PBS targets TSPYL5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag26314 Product name: Recombinant human TSPYL5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-210 aa of BC045630 Sequence: MSGRSRGRKSSRAKNRGKGRAKARVRPAPDDAPRDPDPSQYQSLGEDTQAAQVQAGAGWGGLEAAASAQLLRLGEEAACRLPLDCGLALRARAAGDHGQAAARPGPGKAASLSERLAADTVFVGTAGTVGRPKNAPRVGNRRGPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDAGSGPPATEGSMDTLENVQL Predict reactive species |
| Full Name | TSPY-like 5 |
| Calculated Molecular Weight | 417 aa, 45 kDa |
| Observed Molecular Weight | 45-50 kDa |
| GenBank Accession Number | BC045630 |
| Gene Symbol | TSPYL5 |
| Gene ID (NCBI) | 85453 |
| RRID | AB_3742244 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q86VY4 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
TSPYL5 (Testis-specific Y-encoded-like protein 5) is involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. It is also involved in the regulation of p53/TP53, and suppresses p53/TP53 protein levels and promotes its ubiquitination; Its function is dependent on USP7 and independent on MDM2 (PMID: 20079711; 21170034).
