TXNRD3 Polyclonal antibody, PBS Only

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• TXNRD3 Polyclonal antibody, PBS Only (19517-1-PBS)

• 

  WB analysis using 19517-1-AP (same clone as 19517-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 19517-1-AP (TXNRD3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19517-1-PBS in a different storage buffer formulation.

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  WB analysis of human testis using 19517-1-AP (same clone as 19517-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 19517-1-AP (TXNRD3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19517-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 19517-1-AP (same clone as 19517-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 19517-1-AP (TXNRD3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19517-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 19517-1-AP (same clone as 19517-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 19517-1-AP (TXNRD3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19517-1-PBS in a different storage buffer formulation.

TXNRD3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 19517-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

19517-1-PBS targets TXNRD3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: thioredoxin reductase 3
• Calculated Molecular Weight: 75 kDa
• Observed Molecular Weight: 82 kDa
• GenBank Accession Number: XM_001130163
• Gene Symbol: TXNRD3
• Gene ID (NCBI): 114112
• RRID: AB_10644343
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q86VQ6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TXNRD3, also named as TGR and TRXR3, belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. TXNRD3 displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. TXNRD3 catalyzes the reaction: Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. TXNRD3 promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.