TYK2 Monoclonal antibody
TYK2 Monoclonal Antibody for WB, IF, IHC, ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human and More (1)
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
1E1A10
Cat no : 67411-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HeLa cells, K-562 cells, HEK-293 cells, A549 cells, Jurkat cells, THP-1 cells, HSC-T6 cells |
Positive IHC detected in | human colon cancer tissue, human liver cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Positive IF detected in | HepG2 cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:1000-1:6000 |
Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
Immunofluorescence (IF) | IF : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
WB | See 4 publications below |
Product Information
67411-1-Ig targets TYK2 in WB, IF, IHC, ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Cited Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | TYK2 fusion protein Ag9442 |
Full Name | tyrosine kinase 2 |
Calculated Molecular Weight | 1187 aa, 134 kDa |
Observed Molecular Weight | 134 kDa |
GenBank Accession Number | BC014243 |
Gene Symbol | TYK2 |
Gene ID (NCBI) | 7297 |
RRID | AB_2882652 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
Product Specific Protocols | |
---|---|
WB protocol for TYK2 antibody 67411-1-Ig | Download protocol |
IHC protocol for TYK2 antibody 67411-1-Ig | Download protocol |
IF protocol for TYK2 antibody 67411-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Invest New Drugs IL-10 contributes to gemcitabine resistance in extranodal NK/T-cell lymphoma cells via ABCC4. | ||
bioRxiv SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway. | ||
Cancer Lett HDAC4 mediated LHPP deacetylation enhances its destabilization and promotes the proliferation and metastasis of nasopharyngeal carcinoma |