Thrombospondin 1 Monoclonal antibody

Thrombospondin 1 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

2A3E1

Cat no : 67241-1-Ig

Synonyms

THBS, THBS 1, THBS1, thrombospondin 1, TSP, TSP 1, TSP1



Tested Applications

Positive WB detected inHepG2 cells, NIH/3T3 cells, rat spleen tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

67241-1-Ig targets Thrombospondin 1 in WB,ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Reactivity Human, rat, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Thrombospondin 1 fusion protein Ag29129
Full Name thrombospondin 1
Calculated molecular weight 129 kDa
Observed molecular weight 160 kDa
GenBank accession numberNM_003246
Gene symbol THBS1
Gene ID (NCBI) 7057
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

TSP1, also named as THBS1, THBS and TSP, is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions, and which can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3. TSP1 is a regulator of many biological processes including cell growth, adhesion, migration, platelet aggregation, and fibrin deposition and lysis. It interacts with a number of plasma proteins such as fibrinogen and plasminogen and co-polymerizes with fibrin in clot formation. Secreted TSP1 is a glycoprotein with a molecular mass of 150-180 kDa.

Protocols

Product Specific Protocols
WB protocol for Thrombospondin 1 antibody 67241-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols