Product Information
14457-1-PBS targets UGT1A10 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag6052 Product name: Recombinant human UGT1A10 protein Source: e coli.-derived, PKG Tag: GST Domain: 1-350 aa of BC053576 Sequence: MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVK Predict reactive species |
| Full Name | UDP glucuronosyltransferase 1 family, polypeptide A10 |
| Calculated Molecular Weight | 60 kDa |
| Observed Molecular Weight | 60 kDa |
| GenBank Accession Number | BC053576 |
| Gene Symbol | UGT1A10 |
| Gene ID (NCBI) | 54575 |
| RRID | AB_3669187 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9HAW8 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
UGT1A10 belongs to the superfamily of UDP-glucuronosyltransferases (UGTs) catalyzing the glucuronidation reaction, which is important in the detoxification and enhanced elimination of many endogenous and exogenous substrates. Recently, UGT1A10 was the only enzyme in all 19 known human UGTs to catalyze DA glucuronidation. The UGT1As, among three subfamilies (1A, 2A, and 2B) found in human, share a common C-terminal domain of 245 residues. The N-terminal domains that determine their substrate-binding specificity are variable.
