UNC13B Polyclonal antibody, PBS Only

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• UNC13B Polyclonal antibody, PBS Only (21839-1-PBS)

• 

  WB analysis using 21839-1-AP (same clone as 21839-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21839-1-AP (UNC13B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21839-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 21839-1-AP (same clone as 21839-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21839-1-AP (UNC13B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21839-1-PBS in a different storage buffer formulation.

UNC13B Polyclonal Antibody for WB, Indirect ELISA

Cat No. 21839-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

unc-13 homolog B , Protein unc-13 homolog B, Munc13-2

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Product Information

21839-1-PBS targets UNC13B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag16478

  Product name: Recombinant human UNC13B protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-330 aa of BC111781

  Sequence: MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCSFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLLQGSSRDSCNDSMQSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSHSLSRDGQAGFGEQEKPLEVTGQAEKEAACE

• Full Name: unc-13 homolog B (C. elegans)
• Calculated Molecular Weight: 1610 aa, 183 kDa
• Observed Molecular Weight: 180 kDa
• GenBank Accession Number: BC111781
• Gene Symbol: UNC13B
• Gene ID (NCBI): 10497
• RRID: AB_3669376
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O14795
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

UNC13A is a member of the unliganded-13 (UNC13) family and plays a crucial role in synaptic vesicle priming and exocytosis. UNC13B has been implicated in autism spectrum disorder (ASD), partial epilepsy, and schizophrenia (PMID: 38188011).