Product Information
32375-1-PBS targets USP43 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36448 Product name: Recombinant human USP43 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 900-1123 aa of BC136368 Sequence: CLAPGNSDGPNTARKLKENAGQDIKLPRKFDLPLTVMPSVEHEKPARPEGQKAMNWKESFQMGSKSSPPSPYMGFSGNSKDSRRGTSELDRPLQGTLTLLRSVFRKKENRRNERAEVSPQVPPVSLVSGGLSPAMDGQAPGSPPALRIPEGLARGLGSRLERDVWSAPSSLRLPRKASRAPRGSALGMSQRTVPGEQASYGTFQRVKYHTLSLGRKKTLPESSF Predict reactive species |
| Full Name | ubiquitin specific peptidase 43 |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC136368 |
| Gene Symbol | USP43 |
| Gene ID (NCBI) | 124739 |
| RRID | AB_3742585 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q70EL4 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
USP43 belongs to the DUBs family involved in cancer development and progression.The USPs family is the most recognized group of DUBs, characterized by a wide range of structural and functional variability. The distinguishing features of USPs include the unique catalytic core, known as the histidine and cysteine boxes, as well as the presence of zinc finger domains, ubiquitin-binding domains, or ubiquitin-like domains at the N and/or Ctermini of the catalytic domain (PMID: 16325574). It has 4 isoforms with a molecular weight of 69 kDa, 89 kDa,122 kDa, 123 kDa.
