UTP18 Polyclonal antibody

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  WB analysis using 31055-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31055-1-AP (UTP18 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 31055-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31055-1-AP (UTP18 antibody) at dilution of 1:40000 incubated at room temperature for 1.5 hours.

UTP18 Polyclonal Antibody for WB, ELISA

Cat No. 31055-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

mouse, human

Applications

WB, ELISA

Synonyms

CGI 48, UTP18, WDR50

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Tested Applications

• Positive WB detected in: HeLa cells, mouse brain tissue, mouse kidney tissue, Jurkat cells, SW480 cells

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31055-1-AP targets UTP18 in WB, ELISA applications and shows reactivity with mouse, human samples.

• Tested Reactivity: mouse, human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: UTP18 fusion protein Ag34662
• Full Name: UTP18, small subunit (SSU) processome component, homolog (yeast)
• Calculated Molecular Weight: 62 kDa
• Observed Molecular Weight: 62 kDa
• GenBank Accession Number: NM_016001
• Gene Symbol: UTP18
• Gene ID (NCBI): 51096
• RRID: AB_3669835
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9Y5J1
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

UTP18 (UTP18 small subunit processome component), also known as WDR50. It is expected to be located in nucleus. The protein is one part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. The calculated molecular weight of UTP18 is 62 kDa.