UTX Polyclonal antibody, PBS Only

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• UTX Polyclonal antibody, PBS Only (23984-1-PBS)

• 

  WB analysis of COLO 320 using 23984-1-AP (same clone as 23984-1-PBS)

  COLO 320 cells were subjected to SDS PAGE followed by western blot with 23984-1-AP (UTX antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23984-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 23984-1-AP (same clone as 23984-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 23984-1-AP (UTX antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23984-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 23984-1-AP (same clone as 23984-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23984-1-AP (UTX antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23984-1-PBS in a different storage buffer formulation.

UTX Polyclonal Antibody for WB, Indirect ELISA

Cat No. 23984-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Lysine-specific demethylase 6A, Lysine specific demethylase 6A, KDM6A, Histone demethylase UTX, EC:1.14.11.68

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Product Information

23984-1-PBS targets UTX in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag20018

  Product name: Recombinant human UTX protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1059-1401 aa of BC093868

  Sequence: DHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS

• Full Name: ubiquitously transcribed tetratricopeptide repeat, X chromosome
• Calculated Molecular Weight: 1401 aa, 154 kDa
• Observed Molecular Weight: 154 kDa
• GenBank Accession Number: BC093868
• Gene Symbol: UTX
• Gene ID (NCBI): 7403
• RRID: AB_2935460
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O15550
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

KDM6A, also named UTX, mediates the removal of repressive trimethylation of histone H3, it plays a central role in the regulation of posterior development, by regulating HOX gene expression (PubMed:17851529).