VPS13B Polyclonal antibody, PBS Only

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• VPS13B Polyclonal antibody, PBS Only (24505-1-PBS)

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  IHC staining of human liver using 24505-1-AP (same clone as 24505-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24505-1-AP (VPS13B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24505-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 24505-1-AP (same clone as 24505-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24505-1-AP (VPS13B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24505-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24505-1-AP (same clone as 24505-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24505-1-AP (VPS13B Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 24505-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24505-1-AP (same clone as 24505-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24505-1-AP (VPS13B Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 24505-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 24505-1-AP (same clone as 24505-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using VPS13B antibody (24505-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24505-1-PBS in a different storage buffer formulation.

VPS13B Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Cat No. 24505-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

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Product Information

24505-1-PBS targets VPS13B in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag21368

  Product name: Recombinant human VPS13B protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 64-412 aa of BC132978

  Sequence: ELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYENLNSKMPSVIKIHTLVESLKLSITDQQLPMFIRIMQLGIALYYGEIGNFKEGEIEDLTCHNKDMLGNITGSEDETRIDMQYPAQHKGQELYSQQDEEQPQGWVSWAWSFVPAIVSYDDGEEDFVGNDPASTMHQQKAQTLKDPIVSIGFYCTKATVTFKVGLFSCCLYL

• Full Name: vacuolar protein sorting 13 homolog B (yeast)
• Calculated Molecular Weight: 4022 aa, 449 kDa
• GenBank Accession Number: BC132978
• Gene Symbol: VPS13B
• Gene ID (NCBI): 157680
• RRID: AB_2879579
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q7Z7G8
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

VPS13 (vacuolar protein sorting 13 ) acts at membrane contact sites between intracellular organelles to transport lipids. There are four VPS13 family members in human - VPS13A, VPS13B, VPS13C and VPS13D. Mutations in human VPS13 genes are linked to rare neurodegenerative disorders: chorea- acanthocytosis (VPS13A), Cohen syndrome (VPS13B), predispose to early onset into Parkinson disease (VPS13C) and lead to ataxia/spastic paraplegia (VPS13D) (PMID: 30656912).