Product Information
27128-1-PBS targets VPS37C in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag26024 Product name: Recombinant human VPS37C protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-117 aa of BC141827 Sequence: METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEA Predict reactive species |
| Full Name | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
| Observed Molecular Weight | 39-45 kDa |
| GenBank Accession Number | BC141827 |
| Gene Symbol | VPS37C |
| Gene ID (NCBI) | 55048 |
| RRID | AB_3085928 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | A5D8V6 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
VPS37C (Vacuolar protein sorting-associated protein 37C) is also named as hVps37C, PML39 and ESCRT-I complex subunit VPS37C. VPS37C is a core subunit of the Endosomal sorting complex required for transport-I (ESCRT-I) complex (PMID: 37307706). VPS37C interacts with EKLF and prevents K48-linked polyubiquitination of EKLF and proteasome-mediated EKLF degradation, thus enhancing EKLF protein stability and transcriptional activity (PMID: 37307706).







