Product Information
21056-1-PBS targets VSIG2 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag14342 Product name: Recombinant human VSIG2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 24-243 aa of BC007313 Sequence: VEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVA Predict reactive species |
| Full Name | V-set and immunoglobulin domain containing 2 |
| Calculated Molecular Weight | 327 aa, 34 kDa |
| GenBank Accession Number | BC007313 |
| Gene Symbol | VSIG2 |
| Gene ID (NCBI) | 23584 |
| RRID | AB_3669354 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96IQ7 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
VSIG2, also known as CTXL (cortical thymocyte-like protein), belongs to the V-Set and immunoglobulin (Ig) domain-containing (VSIG) family. The VSIG family is also a member of the immunoglobulin superfamily (IgSF). VSIG2 has been recognized as a novel immune checkpoint that plays a role in regulating immune response. VSIG2 was associated with the development and progression of colon adenocarcinoma (COAD) and pancreatic ductal adenocarcinoma (PDAC) and could be used as a potential biomarker(PMID: 34290531;PMID: 37626304).
