Product Information
33739-1-PBS targets WDHD1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38697 Product name: Recombinant human WDHD1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 950-1129 aa of NM_007086.3 Sequence: SRTTNNEKSPIIKPLIPKPKPKQASAASYFQKRNSQTNKTEEVKEENLKNVLSETPAICPPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMIRFRVLSTEERKVWANKAKGETASEGTEAKKRKRVVDESDETENQEEKAKENLNLSKKQKPLDFSTNQKLSAFAFKQE* Predict reactive species |
| Full Name | WD repeat and HMG-box DNA binding protein 1 |
| Calculated Molecular Weight | 126kDa，1129aa |
| Observed Molecular Weight | 126 kDa |
| GenBank Accession Number | NM_007086.3 |
| Gene Symbol | WDHD1 |
| Gene ID (NCBI) | 11169 |
| RRID | AB_3743064 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | O75717 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
The WD repeat and HMG-box DNA-binding protein 1 (WDHD1), also known as acidic nucleoplasmic DNA-binding protein 1 (AND-1), is a DNA‐binding protein with a total molecular weight of 126 kDa, containing multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WDHD1 contains the highly conserved SepB domain, which plays a crucial role in DNA replication processes(PMID: 37569867). WDHD1 regulates the assembly and activation of the pre‐replication complex (pre-RC), and WDHD1 depletion leads to G1 stagnation and delays progression to the S phase(PMID: 36345604).
