WDR62 Polyclonal antibody, PBS Only

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• WDR62 Polyclonal antibody, PBS Only (23404-1-PBS)

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  IP experiment of HEK-293T using 23404-1-AP (same clone as 23404-1-PBS)

  IP result of anti-WDR62 (IP:23404-1-AP, 4ug; Detection:23404-1-AP 1:500) with HEK-293T cells lysate 1320 ug. This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 23404-1-AP (same clone as 23404-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 23404-1-AP (WDR62 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 23404-1-AP (same clone as 23404-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 23404-1-AP (WDR62 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 using 23404-1-AP (same clone as 23404-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed hTERT-RPE1 cells using WDR62 antibody (23404-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 23404-1-AP (same clone as 23404-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using WDR62 antibody (23404-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

WDR62 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA

Cat No. 23404-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, IP, Indirect ELISA

Synonyms

C19orf14, WD repeat domain 62, WD repeat-containing protein 62

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Product Information

23404-1-PBS targets WDR62 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag19865

  Product name: Recombinant human WDR62 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 281-630 aa of BC017261

  Sequence: CLTSLASCVPASSVLPTDRNLPTPTSAPTPGLAQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQELQAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLLPPVDTQPGVTVPAVSFPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGSTASLLEPTSGALGLFQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVDTGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALLEHYSELLVQAVRRKARGH

• Full Name: WD repeat domain 62
• Calculated Molecular Weight: 1518 aa, 166 kDa
• Observed Molecular Weight: 180 kDa
• GenBank Accession Number: BC017261
• Gene Symbol: WDR62
• Gene ID (NCBI): 284403
• RRID: AB_3085711
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• UNIPROT ID: O43379
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The WD40-repeat protein 62 (WDR62) is a scaffold protein that recruits different components of the JNK signaling pathway to regulate several human diseases including neurological disorders, infertility, and tumorigenesis (PMID: 33937237). Moreover, WDR62 participates in diverse biological processes, especially mitotic spindle organization via regulating centriole biogenesis and the function of centriole-associated protein (PMID: 35093571).